Cannabinoids, The ECS, And Human Body- From An Evolutionary Perspective

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Cannabinoids, The ECS, And Human Body

Takeaway: An apple tree cultivates apples so that primates can eat it and spread apple seeds. Similarly, humans and their biology has evolved over the years from animals to intellectual human beings. Our brains have cannabis receptors in them, how did we get them is still under a lot of debate but one thing is for sure that cannabis has a natural biological connection to our brains. The existence of these receptors is proof that cannabinoids are recognised, needed and used by our bodies. Staple food such as carrot, citrus fruits and broccoli also stimulate our cannabinoid receptors then why are they accepted and cannabis derivatives are not?

Do you think plants produce apples so that you get to enjoy it? If you believe that, you need to gain insight into how evolution works.

They do this to invite the primates for eating it and depositing the seeds along with the essential fertilizers in the nearby region for multiplication. The plants have evolved significantly according to the surrounding ecosystem inclusive of the animals, humans, and birds around them.

Humans, Evolution, and Cannabis

Akin to plants, humans have evolved so remarkably, remarkable to that level that they feel discomfort in sharing their ancestor lines with the apes because you know how embarrassing ‘these’ relatives can be.

But we have central premises of acceptance that we have evolved separately from all other animals, and we believe this to feel special. But what do we feel about our early roots with the plants and kinship with them?

Our DNAs have common ancestors including the wolves, the butterflies, the rafflesias, the sharks, the TREES, etc. Probably this is why our DNAs have cannabis receptors.

There are two kinds of beliefs regarding the cannabis receptors in humans:

  1. First belief talks about how the continuous use of cannabis over the civilizations have resulted in automatic manufacturing of cannabis receptors in the brain. Maybe our body has evolved to make use of the cannabis components or looking at the broader perspective; WE ARE THE KIDS OF CANNABIS PLANTS.
  2. Second belief talks about how humans have incredibly adapted and devised methods to harness the benefit from components of the plants and support the claim that it is purely coincidence to have such receptors in the brains.

A lot of research is yet to be done, and facts are to be uncovered but let’s cover the first believers in this section. They have a definite proof that over the years, our body has progressed mysteriously and its proof lies in the manufacturing of the cannabinoids by it. They believe— pot or not; our brains have the ability to produce their cannabinoids. But what are these substances?

A Cannabinoid is a list of chemical compounds secreted by cannabis flowers which plug-fits exactly into the cannabinoid receptors leading to the excitement of the molecules in the cells resulting in their transmission from one point to the other (neurotransmission).

Generally, all the body receptors rely on the fresh, raw, and unprocessed nutrients. As our DNAs have cannabinoid receptors, it can be concluded that we must have used cannabis plants as raw nutrients for these nutrient longing receptors throughout the evolution.

Since there is an interaction between cannabinoids and cannabinoid receptors, we can note four essential things:

  1. Our body recognizes the cannabinoids
  2. Our body uses the cannabinoids
  3. Our body needs cannabinoids
  4. Our body uses these cannabinoids and provides medical relief. If they were to pose a threat to our bodies, these receptors wouldn’t exist.

The fact that cannabinoid receptors are in the body, it can be confirmed that cannabis must have been used as a staple component in the human diet for over millions of years.

Yin and Yang of the cannabis industry

The cannabinoid class can further be broken down into more than 80 different cannabinoid compounds of which THC and CBD are the two most important constituents.

THC (tetrahydrocannabinol) and CBD (Cannabidiol) are Yin and Yang of the cannabis industry. They are two contradictory but inseparable components. As day-night, old-young, good-bad, male-female, dark-light, etc. exist inseparably, THC and CBD exist due to each other’s existence.

Their interactivity is very contrasting with the receptors. When you consume cannabis with high THC content, the cannabinoid effect is very psychoactive (as it binds the receptors located in the brain) creating recreational and euphoric effect whereas cannabis with high CBD content is not psychotropic, allows respondents to be focused and clear-headed, and interacts with the receptors present in the other parts of the body.

The effect on the body is purely dependent on how the given cannabinoid behaves with the receptors in the body. By agonizing the right cannabinoid receptors by the right cannabinoids, you can attain a wide variety of relief.

Both are considered to have their therapeutic abilities. While THC is observed to look after nauseated and sleep disorders, CBD has indicated positives in responding to the effect of epileptic seizures and other neurological diseases.

One of the interesting observations about CBD is that in case of THC overdose (which may well cause anxious abnormalities and paranoia), CBD is prescribed for muting the effect. Hence, THC and CBD co-relate well with the said Yin and Yang— the existence of contrary forces in the same field.

Cannabinoid potency analysis

As cannabinoid has a myriad of compounds, how do you know which cannabinoid sample has what mixture or what percentage of the compound? As the marijuana battle is slowly reaching a conclusion, a large sector of businesses sees tremendous potential in their economic growth.

Several departments use near-infrared spectroscopy to analyze the cannabinoid compounds in the given sample.

The idea of such analysis is to measure the amount of 9THC, THC-A, CBD, CBD-A, and moisture in the substance and make infused products depending on the amount needed.

It is done by calibrating the white reference with the machine and later placing the granulated product sample in the calibrated hole. You can check out this video for better understanding.

An interesting question.

If you carefully observe the timeline of cannabis history, as the foothold of authority has grown, the character of the cannabis has stigmatized and plummeted sharply. Today, the youth of the society is conditioned to believe the blatant lies, and are convinced to trust the hoaxes hovering over the natural plant.

Technically, the authorities act as walls between the matching of cannabinoid compounds with cannabinoid receptors. They have built this wall because they theorize populist belief, i.e., “cannabis may unleash a beast in man.”

Whatever the situation is, one of the funny and serious questions arise is: a lot of other foodstuff like carrot, citrus fruits, broccoli also stimulate cannabinoid receptors. If cannabis is dangerous for your health, why other foods aren’t?

So, is classifying cannabis as a dangerous product the worst perpetrated lie in the society?

The endocannabinoid system: Waiting to be touched in schools

The endocannabinoid system taught in schools

As mentioned, for some reasons, authorities have shoved their powers for barring the important sessions on endocannabinoid in schools and colleges.

Endocannabinoids are the cannabinoids which are naturally produced in the body and are still not a part of medical curricula.

The cluster of cannabinoid receptors forms the endocannabinoid system. It’s like the cluster of stars in the galaxy relying on the energy to move in the spatial dimension. As soon as the hidden energy works, stars agonize and start traversing like neuro-molecules.

Two of the central receptors are CB1 and CB2. CB1 is dispersed over the central nervous system whereas CB2 receptors are primarily expressed on the tissues and the cells of the immune system. With this, you can conclude that CB2 receptors are present all over the body; hence, cannabis can have a significant effect throughout the body.

A natural process far denounced in the form of taboo?

How justifiable does denouncing a natural process seem like? Various parts of the world consider the natural process— menstruation as taboo. Certain parts of the society see it as an unlucky phenomenon while some think of it as a profane activity.

Similarly, the natural production of the cannabinoids in the body is viewed as an unconsecrated production. Unless we are going to respect the natural prodigy of the human body, we will continue to mock our wisdom.

Instead of asking why are they getting produced naturally, we are wasting our resources in disseminating false beliefs with pre-meditated ideologies.

While evolution takes place naturally, humans can condition people to believe that evolution never occurred. After injecting the century-false data, conditioning is slowly believed as the natural evolution. Conditioning and evolution might mean similar to many, but there is a minor difference, and that little gap has the original key to the truest historical locks.

So, what are your personal take on the cannabinoids and their receptors in the human body? Do you think they are produced by the brain to take advantage of recreational benefits of the cannabinoids? Or is it just a mere coincidence that these receptors bind with the substances?

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